SNP45: Antioxidants – What You Need To Know
For a full list of apps, go here. Or simply search “Sigma Nutrition” in your app of choice. Introduction This is a Premium-exclusive episode of the podcast. To listen to the full episode you need to be subscribed to Sigma Nutrition Premium. What exactly are “antioxidants,” and why do they get so much hype? We […]
SNP42: Is Vitamin A Good or Bad for Bone Health?
For a full list of apps, go here. Or simply search “Sigma Nutrition” in your app of choice.Or listen directly on the Sigma website here. Introduction Vitamin A is often one of the less-discussed micronutrients in relation to bone health, taking a back seat to nutrients like calcium and vitamin D. Yet this fat-soluble vitamin […]
SNP41: Do Certain Foods Really Cause Inflammation – And Are Anti-Inflammatory Diets the Answer?
For a full list of apps, go here. Or simply search “Sigma Nutrition” in your app of choice.Or listen directly on the Sigma website here. Introduction Inflammation has become a nutrition buzzword, often used in extreme or misleading ways. This episode aims to clarify what inflammation is, how it relates to diet and health, and […]
#565: How Zinc Insufficiency Impacts Inflammation, Immunity & Aging – Prof. Emily Ho
Listen Here: For a full list of apps, go here. Or simply search “Sigma Nutrition” in your app of choice.Or listen directly on the Sigma website here. Introduction Zinc is an essential micronutrient that often flies under the radar, despite being vital for hundreds of enzymes and transcription factors involved in immunity, antioxidant defense, and […]
#560: Neurodiversity & Nutrition: Choline, ADHD, Dyslexia, and Beyond – Emma Derbyshire, PhD
Listen Here: For a full list of apps, go here. Or simply search “Sigma Nutrition” in your app of choice.Or listen directly on the Sigma website here. Introduction Nutrition is increasingly being considered as a modifiable factor that may influence neurodevelopmental outcomes. While severe deficiencies in certain nutrients are known to have dramatic effects, there […]
Multivitamin Nihilism: Is it Actually Worthless to Supplement? (SNP37)
Multivitamin and multimineral supplements have long been a topic of both scientific inquiry and public debate. While they are often marketed as convenient solutions for achieving nutritional adequacy, their true value remains contentious. Are these supplements essential insurance policies against nutrient deficiencies, or are they merely expensive placebos?
#544: Genetic Variants and Response to Nutrients – Martin Kohlmeier, MD PhD
Listen Here: For a full list of apps, go here. Or simply search “Sigma Nutrition” in your app of choice.Or listen directly on the Sigma website here. Introduction In the realm of nutrition science, individual differences are more profound and impactful than many realize. For decades, we’ve developed dietary recommendations with a “one-size-fits-all” approach, assuming […]
#543: Eye Health & Nutrition – Prof. John Nolan
Listen Here: For a full list of apps, go here. Or simply search “Sigma Nutrition” in your app of choice.Or listen directly on the Sigma website here. Introduction In this episode, we dive deep into the world of ocular nutrition with Professor John Nolan, exploring how specific nutrients can play crucial roles in preserving eye […]
#521: How Does Coffee Impact Our Health?
The relationship between coffee and health is complex, encompassing areas like blood lipids, cardiovascular disease, neurodegenerative diseases, anxiety, and depression. Coffee has an interesting nutrient profile and contains diverse bioactive compounds that influence metabolism.
#496: ATBC Cancer Prevention Study – Crucial Lessons
The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study (ATBC) stands as a seminal and pioneering research endeavor within the domain of epidemiology and cancer prevention. Conducted in Finland, the study aimed to examine the potential protective effects of alpha-tocopherol (vitamin E) and beta-carotene supplementation against the occurrence of various cancer types, particularly lung cancer, among male smokers.
#467: Iron Issues in Athletes – Prof. Pete Peeling
In this episode, Professor Pete Peeling of the University of Western Australia discusses the role of iron in performance, iron deficiency in athletes, the impact of exercise-induced inflammation, and other important issues.
#466: Iron Absorption from Foods & Supplements – Prof. Paul Sharp
To discuss some of the nuances of iron bioavailability, absorption, and metabolism, leading expert in the area Professor Paul Sharp of King’s College London is on the podcast. Prof. Sharp discusses crucial aspects of dietary iron sources, bioavailability, supplementation, and impacts in the body.
#465: Diagnosing & Treating Iron Deficiency & Excess – Austin Baraki, MD
So how is iron status measured? Where can errors in diagnosis occur? What problems arise with iron deficiency and iron overload? Dr. Austin Baraki provides some answers.
#451: Potassium & Blood Pressure: Influence of Sex & Sodium
It has been consistently shown in research that elevated dietary sodium consumption is associated with high blood pressure and an increased risk of cardiovascular disease. In addition, low levels of dietary potassium intake are associated with these same risks. However, there is some debate on how to characterize these relationships.
In a study published in European Heart Journal in July 2022, using data from the EPIC-Norfolk study, researchers attempted to answer whether the associations between potassium and both blood pressure and cardiovascular disease: 1) differ between men and women? and 2) depend on daily sodium intake.
In this episode Dr. Alan Flanagan and Danny Lennon discuss the details of this study and then link it to the overall evidence base and what this may mean for potassium (and sodium) intake considerations.
#444: Folate – Intake, Genetics & Health Outcomes
Folate (also known as viatmin B9) actually relates to a collection of folates; both natural dietary folates and synthetic forms, primarily folic acid. This folate/folic acid that is consumed via the diet or supplementation is a precursor for the formation of tetrahydrofolate (THF), which is a carbon donor and acts a cofactor for a number of enzymes that play important roles in several processes. In this episode, Alan and Danny discuss the role of folate in the methlyation cycle, the impact of folate insufficiency/deficiency, genetics variatnts of the MTHFR gene (and other genes) that impact folate metabolism, and the impact of folate on health outcomes; including heart disease, birth defects, cancer, and brain health & cognition.
#443: Kevin Klatt, PhD, RD – Can Choline Help Improve DHA Status?
A recently published study by Klatt and colleagues examined the impact of choline supplementation alongside DHA supplementation, versus DHA supplementation alone, on DHA status in pregnancy. It is known that DHA is a critical nutrient at this time for healthy development of the child. And through a number of mechanisms discussed later, it has been hypothesized that choline could lead to greater DHA status.
#407: Polyphenols – Impact on Blood Pressure, Endothelial Function & Heart Disease Risk
In this episode we discuss the potential impact of dietary polyphenols on cardiovascular disease risk; including impacts on blood pressure, flow-mediated dilation, and other related outcomes. We talk about some potential mechanisms and then several specific randomized, controlled trials.
#406: Polyphenols & Cognitive Health
In this episode we discuss the potential impact of dietary polyphenols on cognitive health; including cogitnitve funciton, memory, and risk of dementia and Alzeimher’s. We talk about some potential mechanisms, cohort studies, and then direct controlled trials.