Tag: Obesity

#583: Ultra-Processed Foods & Fixing the Food Environment – Kevin Hall, PhD

Listen Here: For a full list of apps, go here. Or simply search “Sigma Nutrition” in your app of choice.Or listen directly on the Sigma website here. Introduction Ultra-processed foods have become central to the way we eat and to many of the challenges we face in public health nutrition. They dominate supermarket shelves, shape […]

SNP43: The Brain’s Role in Energy Intake & Eating Behaviour

For a full list of apps, go here. Or simply search “Sigma Nutrition” in your app of choice.Or listen directly on the Sigma website here. Introduction In this solo episode, Danny discusses a chapter of the book Food Intelligence, co-authored by Julia Belluz and Kevin Hall. This chapter, titled “The Conductor”, focuses on how the […]

#570: Fructose: Metabolism, Claims & Context for Risk – Scott Harding, PhD

Listen Here: For a full list of apps, go here. Or simply search “Sigma Nutrition” in your app of choice.Or listen directly on the Sigma website here. Introduction Fructose has often been labeled a uniquely damaging nutrient, blamed for obesity, diabetes, and other metabolic diseases. But does fructose truly have unique harmful effects or are […]

#566: Can We Maintain Weight Loss? Pharmacology and Behavior – Tara Schmidt, RD

Listen Here: For a full list of apps, go here. Or simply search “Sigma Nutrition” in your app of choice.Or listen directly on the Sigma website here. Introduction GLP-1 receptor agonists have changed the landscape of obesity treatment, offering levels of weight loss once thought unattainable without surgery. But what happens after the weight is […]

#557: Health Psychology & Eating Behaviour – Prof. Jane Ogden

Listen Here: For a full list of apps, go here. Or simply search “Sigma Nutrition” in your app of choice.Or listen directly on the Sigma website here. Introduction In the realm of health psychology, our understanding of eating behaviors extends beyond mere physiological hunger cues. Research indicates that factors such as learned associations, cultural influences, […]

Timing of Eating: Energetic Hypothesis (SNP32)

In the ongoing exploration of weight loss strategies, the timing of food intake has emerged as a fascinating area of study. While traditional advice often focuses on what we eat, growing evidence suggests that when we eat could also play a crucial role in weight management. This concept, known as chrononutrition, examines how our body’s internal clock influences the metabolic processes associated with food intake. Could adjusting meal times offer a new pathway to effective weight loss?

#526: Eating Rate, Food Texture & Satiation – Marlou Lasschuijt, PhD

Food science and behavior are intimately connected. One critical but often overlooked facet of this connection is food texture and its substantial impact on eating behavior and energy intake. Food texture encompasses characteristics such as hardness and structure. It categorizes food into liquids, semi-solids, and solids, each with a wide range of textures—from dry and crispy to elastic and more substantial. This classification deeply affects how we consume food. The time it takes to chew and swallow a food item can vary greatly based on its texture.

#498: The PROPEL Trial & Weight Loss Interventions in Primary Care – John Apolzan, PhD

The PROPEL (Promoting Successful Weight Loss in Primary Care in Louisiana) trial was a cluster-randomized weight loss trial is specifically tailored to address the pressing health concerns of an underserved population in Louisiana, where obesity rates have reached alarming levels. In this episode we have the opportunity to delve deeper into the intricacies of the PROPEL trial and gain insights from one of its lead researchers, Dr. John Apolzan of the Pennington Biomedical Research Center.

#460: Dr. Priya Sumithran – Body Fat Regulation, Pros & Cons of Weight Loss Interventions, and GLP-1 Receptor Agonists

In this episode, Dr. Priya Sumithran discusses this physiologic control of body mass, in addition to environmental and behavioural factors that make weight loss maintenance difficult. Dr. Sumithran also discusses what this means for setting weight loss targets, choosing the correct intervention, and looking to non-weight-centric approaches for certain individuals. We also discuss the evidence on GLP-1 receptor agonist drugs, such as Semaglutide, as a treatment for obesity.

#429: Kevin Hall, PhD & Stephan Guyenet, PhD – Carbohydrate-Insulin Model vs. Energy Balance Model

The pathogenesis of obesity is clearly complex. And the need to have a comprehensive model to explain this pathogenesis is important. One such model, termed the Energy Balance Model, has largely been the consensus paradigm of obesity scientists to this point. However, there are others who propose that this is not the correct model of obesity, but rather that obesity pathogenesis can be better explained by a model called the Carbohydrate-Insulin Model (CIM) of obesity.

#395: Prof. Carel Le Roux – Current Thinking in Obesity Treatment

Professor le Roux is an expert in metabolic medicine and is currently a Professor of Experimental Pathology, University College Dublin. He is recognised as a world leader in metabolism and obesity. Professor le Roux’s clinical focus is in the management of Type 2 diabetes, pre-diabetes, obesity, cardiovascular risk and other metabolic disorders. Professor Carel le Roux has been published extensively and currently holds a number of editorial roles for journals in his field including, Clinical Obesity and Surgery for Obesity and Related Diseases.

#391: Is There a Body Weight Set Point?: Models of Body Mass Regulation

In this episode Danny and Alan discuss the three primary models used to explain body mass regulation: 1) Set Point Model, 2) Settling Point Model, 3) Dual Intervention Model. They discuss the role of feedback systems, environment, behaviour, as well as discussing both the “thrifty gene hypothesis” and John Speakman’s “drifty gene hypothesis”.

#388: Consequences of Weight Stigma and Weight Bias

Danny & Alan discuss the current evidence on the health consequences and societal consequences of weight stigma and weigh bias. This includes implicit bias, explicit bias, and internalization of bias. What evidence do we currently have? And what questions remain unanswered?

#379: Obesity & Chronic Disease Risk with Dr. Spencer Nadolsky

Guest Information Spencer Nadolsky, DO Dr. Spencer Nadolsky is a board-certified obesity specialist, lipidologist, and family physician. Dr. Spencer uses lifestyle as medicine to treat and prevent chronic disease via telemedicine. He speaks all around the world about weight loss and health and is also the author of The Fat Loss Prescription and The Natural Way […]

#331: Prof. Roy Taylor – Diabetes Remission, Very-low Calorie Diets & the Twin Cycle Hypothesis

Guest Information Prof. Roy Taylor, MB ChB, MD Roy Taylor is Professor of Medicine and Metabolism at the University of Newcastle in the UK. There he is also director of the Newcastle Magnetic Resonance Centre. Prof. Taylor is an Honorary Consultant Physician at Newcastle Acute Hospitals NHS Trust. Since publishing his “twin cycle” hypothesis of […]

#324: Fatima Cody Stanford, MD – Obesity Treatment & Weight Bias

Find the podcast on your app of choice hereGuest Information Fatima Cody Stanford, MD, MPH, MPA Dr. Fatima Cody Stanford is an obesity medicine physician, scientist, educator, and policy maker at Massachusetts General Hospital and Harvard Medical School. She is a national and international sought after expert in obesity medicine who bridges the intersection of […]